4-Aminophenol CAS 123-30-8 Purity >99.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of 4-Aminophenol (p-Aminophenol) (CAS: 123-30-8) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase 4-Aminophenol, Please contact: alvin@ruifuchem.com
Chemical Name | 4-Aminophenol |
Synonyms | p-Aminophenol; Para-Aminophenol; 4-Hydroxyaniline; p-Hydroxyaniline; 4-Amino-1-Hydroxybenzene; p-Hydroxyphenylamine; 4-Hydroxyphenylamine; 4-Hydroxybenzenamine; 1-Amino-4-Hydroxybenzene; Paracetamol EP Impurity K; Mesalazine EP Impurity A |
Stock Status | In Stock, Commercial Production |
CAS Number | 123-30-8 |
Molecular Formula | C6H7NO |
Molecular Weight | 109.13 g/mol |
Melting Point | 186.0~189.0℃ |
Boiling Point | 284℃ |
Flash Point | 195℃(383°F) |
Density | 1.29 |
Sensitive | Light Sensitive, Air Sensitive, Heat Sensitive |
Water Solubility | Slightly Soluble in Water |
Solubility in Hot HCl (1+3) | Almost Transparency |
Solubility | Slightly Soluble in Ether, Alcohol. insoluble in Chloroform, Benzene |
Stability | Stable, Though May Discolour in Air. Incompatible with Acids, Chloroformates, Strong Oxidizing Agents. |
Hazard Class | 6.1; Poison |
Packing Group | III |
COA & MSDS | Available |
Sample | Available |
Origin | Shanghai, China |
Shelf Life | 24 Months if Stored Properly |
Brand | Ruifu Chemical |
Items | Specifications | Results |
Appearance | Cream-Coloured to White Crystallization or Powder | Complies |
4-Aminophenol Purity | >99.0% (HPLC) | 99.86% |
Melting Point | 186.0~189.0℃ | 187.3℃ |
Water by Karl Fischer | <0.50% | 0.36% |
Ferrous Content | <0.005% | 0.001% |
Transmittance | >95.0% | 98.8% |
Para-Nitrophenol | <0.50% | Not Detected |
Any Other Impurity | <0.50% | Complies |
Total Impurities | <1.00% | 0.14% |
Infrared Spectrum | Consistent with Structure | Complies |
Conclusion | The product has been tested and complies with the given specifications |
Package: Fluorinated Bottle, 25kg/Bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry and well-ventilated warehouse away from incompatible substances. Protect from light and moisture. Incompatible with acids, chloroformates and strong oxidizing agents. Stored separately from oxidants and food additives.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
Risk Codes R20/22 - Harmful by inhalation and if swallowed.
R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
R68 - Possible risk of irreversible effects
R40 - Limited evidence of a carcinogenic effect
Safety Description S28 - After contact with skin, wash immediately with plenty of soap-suds.
S36/37 - Wear suitable protective clothing and gloves.
S60 - This material and its container must be disposed of as hazardous waste.
S61 - Avoid release to the environment. Refer to special instructions / safety data sheets.
S28A -
UN IDs UN 2512 6.1/PG 3
WGK Germany 3
RTECS SJ5075000
FLUKA BRAND F CODES 8
TSCA Yes
HS Code 2922299090
Hazard Class 6.1
Packing Group III
Toxicity LD50 orally in Rabbit: 375 mg/kg LD50 dermal Rabbit > 10000 mg/kg
4-Aminophenol (p-Aminophenol) (CAS: 123-30-8) is the organic compound with the formula H2NC6H4OH, belongs to the class of organic compounds known as aniline and substituted anilines. 4-Aminophenol turns tan to brown on exposure to air. slightly soluble in water and ethanol, insoluble in benzene and chloroform, and quickly turns brown when dissolved in lye. Used as pharmaceutical intermediates, rubber antioxidant, photographic developer and dyestuff.
4-Aminophenol is widely used in the synthesis of pharmaceuticals, dyes and other organic products and is mainly for the synthesis of paracetamol, clofibrate ketone, vitamin B1 and compound nicotinamide. Use as raw materials, antioxidants and developers for medicines and dyes. It can be used for the production of Sulphur Blue FBG and weak acid dyes such as yellow 5G. The product is the intermediate of pharmaceutical intermediates, dyes and other fine chemicals. It can be used for the production of paracetamol, azo dyes, sulfur dyes, acid dyes, fur dye and developer, antioxidants as well as oil additive. It can be used for gold assay as well as determination of copper, iron, magnesium, vanadium, nitrite and cyanate, antioxidants. p-Aminophenol is an oxidative hair dye precursor. It is incorporated in oxidative hair dye formulations.
It is toxic. The p-Aminophenol has double toxicity of both aniline and phenol. Absorption of it through the skin can cause dermatitis as well as cause methemoglobinemia and asthma. The contact of its hydrochloride with the skin can cause severe itching or eczema.
Heat (decomposition forming HCN, nitrous vapors, CO); water (CO2); reacts violently with acids, bases, alcohols and amines causing fire and explosion hazards [Handling Chemicals Safely 1980 p. 647].
Poison by ingestion, subcutaneous, and intraperitoneal routes. An experimental teratogen. Other experimental reproductive effects. An allergen and skin and eye irritant. Mutation data reported. Can cause contact dermatitis, bronchial asthma, and methemoglobinemia with cyanosis. When heated to decomposition it emits toxic fumes of NOx,.
UN2512 Aminophenols (o-; m-; p-), Hazard Class: 6.1; Labels: 6.1-Poisonous materials
These phenol/cresol materials can react with oxidizers; reaction may be violent. Incompatible with strong reducing substances such as alkali metals, hydrides, nitrides, and sulfides. Flammable gas (H2) may be generated, and the heat of the reaction may cause the gas to ignite and explode. Heat may be generated by the acidbase reaction with bases; such heating may initiate polymerization of the organic compound. Reacts with boranes, alkalies, aliphatic amines, amides, nitric acid, sulfuric acid. Phenols are sulfonated very readily (e.g., by concentrated sulfuric acid at room temperature). These reactions generate heat. Phenols are also nitrated very rapidly, even by dilute nitric acid and can explode when heated. Many phenols form metal salts that may be detonated by mild shock.