(R)-Diphenylprolinol CAS 22348-32-9 Purity ≥99.0% e.e ≥99.0% Dapoxetine Hydrochloride Intermediate Factory

Short Description:

Chemical Name: (R)-Diphenylprolinol 

CAS: 22348-32-9

Appearance: White Crystal

Purity: ≥99.0%  e.e: ≥99.0% 

Intermediate of Dapoxetine Hydrochloride (CAS: 129938-20-1) in the treatment of Premature Ejaculation in Men (PE) 

Enquiry: alvin@ruifuchem.com


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Description:

Chemical Properties:

Chemical Name (R)-Diphenylprolinol
Synonyms (R)-(+)-α,α-Diphenyl-2-Pyrrolidinemethanol;(R)-(+)-2-(Diphenylhydroxymethyl)pyrrolidine; (R)-(+)- α,α-Diphenylprolinol; (R)-1,1-Diphenylprolinol; (R)-(+)-Diphenyl-2-Pyrrolidinemethanol
CAS Number 22348-32-9
CAT Number RF-CC114
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C17H19NO
Molecular Weight 253.35
Solubility in Chloroform Almost Transparency
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance White Crystal 
Identification HPLC; IR
Purity ≥99.0%
e.e ≥99.0%
Specific Rotation [α]D20 +66.0°~ +68.0° (C=3, MeOH 25℃)
Melting Point 77.0~81.0℃
Loss on Drying ≤0.50%
Single Impurity ≤0.50%
Total Impurities ≤1.0%
Heavy Metals  ≤20ppm
Test Standard Enterprise Standard
Usage Chiral Compounds; Pharmaceutical Intermediates

Package & Storage:

Package: Bottle, Cardboard Drum, 25kg/Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

Advantages:

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FAQ:

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Application:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of (R)-Diphenylprolinol (CAS:  22348-32-9) with high quality. Shanghai Ruifu Chemical Co., Ltd. plays an important role in the chiral chemistry, the company is committed to the production of chiral compounds. Our products are widely praised by customers. 

(R)-Diphenylprolinol (CAS 22348-32-9) can be used in the synthesis of Dapoxetine Hydrochloride (CAS 129938-20-1). Dapoxetine Hydrochloride is a short-acting novel selective serotonin reuptake inhibitor marketed for the treatment of premature ejaculation (PE) in men. PE is the most common male sexual disorder. 

(R)-Diphenylprolinol (CAS 22348-32-9) is the (R)-enantiomer of Diphenylprolinol, a relatively mild norepinephrine-dopamine reuptake inhibitor. (R)-α,α-Diphenylprolinol is more pharmacologically active than its (S)-enatiomer. (R)-Diphenylprolinol can be used for the preparation of the corresponding oxazolidine borane, the compound can be used for borane-mediated asymmetric reduction of ketone.

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